Analytical Laboratory National Horizons Centre

Background
Features and Capabilities
LC-MS instrumentation
GC-MS instrumentation
Other Instrumentation
Software
Contact

Background:

Established in 2019, the Analytical Laboratory contains state-of-the-art equipment with wide analytical capabilities.

The laboratory has been recognised as a Waters Centre for Innovation.

Features and Capabilities

Separation: Ultra Performance Liquid Chromatography (UPLC), Gas Chromatography (GC)

Ionisation: Electrospray Ionisation (ESI), Atmospheric Pressure Chemical Ionisation (APCI), Electron Impact Ionisation (EI), Chemical Ionisation (CI), Matrix Assisted Laser Desorption Ionisation (MALDI),

Mass Analysis: Single Quadrupole, Triple Quadrupole, Time-Of-Flight (ToF)

LC-MS Instrumentation

Xevo G2-XS
Synapt G2-Si
Cyclic IMS
Xevo TQ-S Micro

Xevo G2-XS

Configuration: Acquity I-Class UPLC system coupled to QToF mass spectrometer

Ionisation: ESI, APCI

Manufacturer: Waters

Synapt G2-Si

Configuration: Acquity M-Class UPLC system coupled to an Q-ToF Ion Mobility Spectrometry (IMS) mass spectrometer

Ionisation: ESI, APCI, ASAP, DESI, MALDI, API

Mo

Manufacturer: Waters

Cyclic IMS

Configuration: Acquity H-Class UPLC system coupled to a QToF cyclic Ion Mobility (IMS) mass spectrometer

Ionisation: ESI, API, ASAP

Manufacturer: Waters

Travelling Wave Ion Mobility Spectrometry (TWIMS) on the Cyclic IMS. The Cyclic IM device allows high resolution, multi-pass separation of analytes, based on shape as well as m/z

Xevo TQ-S Micro

Configuration: Acquity H-Class UPLC system coupled to triple quadrupole mass spectrometer

Ionisation: ESI, API

Manufacturer: Waters

GC-MS Instrumentation

ISQ 7000 GC-MS
Xevo TQ GC-MS

ISQ 7000 GC-MS

Configuration: Trace 1300 series Gas Chromatography (GC) system coupled to a single quadrupole mass spectrometer

Ionisation: Electron Ionisation (EI)

Manufacturer: Thermo Scientific

Xevo TQ GC-MS

Configuration: Gas Chromatography (GC) system coupled to a Triple Quadrupole mass spectrometer

Ionisation: Electron Ionisation (EI)

Manufacturer: Waters and Agilent

Other Instrumentation

Acquity UPLC system
GC-FID

Acquity UPLC System

Configuration: Acquity H-Class UPLC instrument with fraction collector

Detection: Fluorescence and Photo Diode Array

Manufacturer: Waters

GC-FID

Configuration: Standalone GC instrument

Detection: Flame Ionisation

Manufacturer: Waters

Software

Progenesis QI: advanced data analysis package for lipidomics and metabolomics

Progenesis QI for Proteomics: advanced proteomics research tool for label-free quantitative analysis

Mass Lynx V4.2: controls Waters instrumentation for analysis and processing of raw data

Drift Scope:  Automates detection of components from 3D or 4D datasets to facilitate interpretation

PEAKS Studio X Pro: protein identification, quantification and PTM analysis

Mascot Server: protein identification, peptide mass fingerprinting and MS/MS database searching

Protein Lynx Global Server (PLGS): quantitative and qualitative data processing and interpretation

Gaussian 16W: computational chemistry modelling

Avogadro: Molecular editor and visualiser