Investing in the Global Fund partnership is one of the most effective ways to save lives, improve the health of many and reinforce global health security.
In 2024, the Global Fund partnership – led by country partners, communities affected by the diseases and frontline health workers – continued to decisively advance the fight against AIDS, tuberculosis (TB) and malaria. In countries where the Global Fund invests, the combined incidence rate from the three diseases has reduced by 42% since 2002 and the combined death rate by 63% over the same period, saving 70 million lives.
But after decades of progress, global health is in crisis. Declining international funding is jeopardizing the fight against AIDS, TB and malaria – and with it, global health security. Meeting this challenge requires smart investments, bold new thinking and a shared commitment to ending these diseases as public health threats.
Table of Contents
Results Report
- 2025 Global Fund Results Report (English and Français)
- At a Glance (English and Français)
- Press Release (English and Français)
Results at a Glance
- 70 Million Lives Saved
- State of the Fight: HIV
- State of the Fight: Tuberculosis
- State of the Fight: Malaria
- Health and Community Systems
- Agility and Resilience in the Face of Crises
- Investing for Impact
Case Studies
- Namibia: Transforming the HIV Response for Young People
- The Philippines: Meet Anthony Estomata, a Specimen Transport Rider (STRider)
- Nigeria: Deploying the Latest Tools to Prevent Child Deaths from Malaria
- West Africa: Bolstering Early Warning Disease Detection
- Ukraine: Delivering Lifesaving Care Despite the War
- Ethiopia: Meet Fanose, Health Extension Worker
Social Media Messages
The Global Fund's Eighth Replenishment: The Path Ahead
Data Explorer
Investments in health not only save lives – they also drive economic productivity and broader socioeconomic development.
Global Fund 2025 Results Report
70 Million Lives Saved
Health programs supported by the Global Fund partnership have saved 70 million lives as of the end of 2024.
Over the past two decades, working hand in hand with communities most affected by the three diseases, governments (implementers and donors), the private sector, civil society and technical partners, the combined death rate from AIDS, TB and malaria has fallen by 63%.
These investments in health not only save lives – they also drive economic productivity and broader socioeconomic development.
Social Media Post: The @GlobalFund 2025 Results Report is now available. Working together, the Global Fund partnership has saved 70 MILLION lives since 2002. Investing in the Global Fund is one of the most effective ways to save lives, improve the health of many and reinforce global health security. Learn more: https://www.theglobalfund.org/en/results/
In countries where the Global Fund invests, the combined incidence rate from AIDS, TB and malaria has reduced by 42% since 2002 and the combined death rate by 63%.
Global Fund 2025 Results Report
Results at a Glance
State of the Fight: HIV
The Global Fund provides 26% of all international financing for HIV programs.
In 2024, the Global Fund supported access to prevention options and committed to reaching 2 million people with lenacapavir, a breakthrough in HIV prevention.
The Global Fund invested in tackling barriers to HIV services, expanding community‑led testing, tailoring care for people living with HIV and expanding access to better‑tolerated treatments.
- 46.6 million HIV tests were taken.
- 12.3 million people were reached with HIV prevention services in 2024.
- 25.6 million people were on lifesaving antiretroviral therapy for HIV in 2024.
- 1.4 million people received antiretroviral pre-exposures prophylaxis (PrEP) in 2024.
- 648,000 mothers living with HIV received medicine to keep them alive and prevent transmitting HIV to their babies in 2024.
Social Media Post: New @GlobalFund Results: 25.6 million people were on lifesaving antiretroviral therapy for HIV in 2024. Working together, the Global Fund partnership is aligning efforts, scaling proven solutions and delivering impact in the fight against AIDS. Learn more: https://www.theglobalfund.org/en/results/#hiv
The Global Fund works closely with partners to align efforts, scale proven solutions and deliver impact in the fight against AIDS.
Global Fund 2025 Results Report
Results at a Glance
State of the Fight: Tuberculosis
The Global Fund provides 73% of all international financing for TB programs.
In 2024, the Global Fund supported efficient, equitable and cost���effective interventions for people at highest risk – finding and treating “missing” people with TB, bringing services to hard‑to‑reach communities, expanding access to better treatment regimens and fighting drug‑resistant TB.
The Global Fund also backed innovative tools like AI‑powered detection and portable digital chest X‑rays, and increased access to more affordable TB commodities.
- 7.4 million people were treated for TB in 2024.
- 317,000 people living with HIV and TB were on antiretroviral therapy during TB treatment in 2024.
- 3.4 million people exposed to TB received preventive therapy in 2024.
- 120,000 people were on treatment for drug-resistant TB in 2024.
Social Media Post: New @GlobalFund Results: 7.4 million people were treated for tuberculosis in 2024. The Global Fund partnership is working hand-in-hand with governments, civil society, the private sector and community-based organizations to make TB services efficient, equitable and effective. Learn more: https://www.theglobalfund.org/en/results/#tb
The Global Fund works hand-in-hand with governments, civil society, the private sector and community-based organizations to make TB services efficient, equitable and effective.
Global Fund 2025 Results Report
Results at a Glance
State of the Fight: Malaria
The Global Fund provides 59% of all international financing for malaria programs.
In 2024, we supported community health workers and locally driven solutions to reach those most vulnerable, while strengthening access to testing, treatment and prevention options like seasonal malaria chemoprevention for children and medicines for pregnant women.
The Global Fund’s market‑shaping efforts accelerated the scale-up of dual active ingredient insecticide-treated nets. The Global Fund also continued supporting countries to fight drug and insecticide resistance and respond to evolving environmental and entomological threats.
- 360 million suspected cases of malaria were tested in 2024.
- 50.9 million children received seasonal malaria chemoprevention in 2024.
- 173 million cases of malaria were treated in 2024.
- 17.8 million pregnant women received preventive treatment in 2024.
- 162 million insecticide-treated mosquito nets were distributed to protect families from malaria in 2024.
Social Media Post: New @GlobalFund Results: 162 million mosquito nets were distributed to protect families from malaria in 2024. Working together, the Global Fund partnership is prioritizing local solutions that build long-term resilience to better withstand future threats. Learn more: https://www.theglobalfund.org/en/results/#malaria
The Global Fund supported malaria programs prioritize local solutions that build long-term resilience to better withstand future threats.
2025 Global Fund Results Report
Health and Community Systems
The best global defense against infectious diseases is to contain outbreaks at their source through strong, resilient health systems.
Global Fund investments in health systems and disease surveillance in more than 100 countries help detect, track and contain new outbreaks around the world.
In 2024, the Global Fund invested US$2.7 billion in these areas, part of the US$6.1 billion we are investing between 2024-2026 – a 49% increase over the previous grant cycle and the largest health systems investment in Global Fund history. This makes the Global Fund the largest provider of external grants for reinforcing pandemic preparedness and response.
Social Media Post: The best global defense against infectious diseases is to contain outbreaks at their source through strong, resilient health systems. @GlobalFund invests in health systems and disease surveillance in more than 100 countries help detect, track and contain new outbreaks around the world. Learn more: https://www.theglobalfund.org/en/results/#hcs
The best global defense against infectious diseases is to contain outbreaks at their source through strong, resilient health systems.
2025 Global Fund Results Report
Agility and Resilience in the Face of Crisis
Born out of crisis and built for resilience, the Global Fund partnership has, over the last 23 years, unwaveringly pursued its mission to end AIDS, TB and malaria as public health threats, despite numerous challenges. Conflict and displacement, the erosion of human rights, economic instability, deepening inequalities and an increase in extreme weather events all fuel the spread of disease and disrupt response efforts.
Despite these immense challenges, the Global Fund remains committed and determined. Time and again, crises have tested our resolve, and time and again, the Global Fund partnership has responded with resilience and agility.
Social Media Post: The @GlobalFund 2025 Results Report is now available. Working together, the Global Fund partnership has saved 70 MILLION lives since 2002. Investing in the Global Fund is one of the most effective ways to save lives, improve the health of many and reinforce global health security. Learn more: https://www.theglobalfund.org/en/results/#crises
As we navigate profound changes in the global health landscape, we must be relentless in our pursuit of solutions and opportunities.
2025 Global Fund Results Report
Investing for Impact
The Global Fund works directly with countries to ensure every dollar we invest drives the greatest possible impact. However, the convergence of funding reductions with multiple other challenges threatens the hard-won progress we have achieved over the past two decades placing millions of lives at risk.
While international funding will remain essential in the near term to sustain impact and programmatic progress, we must accelerate efforts to strengthen domestic financing, raise additional resources, maximize the effectiveness of existing resources, better support countries to transition from external financing, and engage the private sector to play a larger role.
The Global Fund is committed to leading this effort, drawing on deep experience and the unique ability to bring partners together in pursuit of shared goals.
Social Media Post: Just Released: 2025 Global Fund Results Report. Working together, the Global Fund partnership has saved 70 MILLION lives since 2002. Investments in health not only save lives – they also drive economic productivity and broader socioeconomic development. Learn more: https://www.theglobalfund.org/en/results/#impact
The Global Fund works directly with countries to ensure every dollar invested drives the greatest possible impact.
2025 Global Fund Results Report
Case Study: Namibia
Transforming the HIV Response for Young People
In Namibia, young women remain disproportionately affected by HIV, facing higher risks due to social and economic vulnerabilities, limited access to services and gender-based violence.
The Global Fund and partners support a comprehensive, youth-focused response that is helping close critical gaps in HIV prevention and care. This includes HIV testing, access to PrEP and condoms, treatment for sexually transmitted infections, mental health support and referrals for those who experience gender-based violence.
Namibia has made major strides in fighting HIV: Over 90% of people living with HIV know their status, the vast majority are on treatment, and most are virally suppressed. Since 2013, new HIV infections have nearly been cut in half.
Social Media Post: Namibia is making major strides in the fight against HIV: Over 90% of people living with HIV know their status, the vast majority are on treatment, and most are virally suppressed. Since 2013, new HIV infections have nearly been cut in half. Learn more: https://www.theglobalfund.org/en/stories/2025/2025-09-10-namibia-transforming-hiv-response-young-people/
Case Study: The Philippines
Meet Anthony Estomata, a Specimen Transport Rider (STRider)
Anthony Estomata plays an important role in the fight against TB in the Philippines.
As 1 of 400 Specimen Transport Riders (STRiders) across the Philippines, Anthony uses his motorcycle to transport sputum specimens from clinics to laboratories equipped with GeneXpert diagnostic machines – helping speed up testing and treatment in areas burdened by traffic congestion.
STRiders, who work alongside government health facility teams, are part of a nationwide initiative supported by the Global Fund and the Philippine Business for Social Progress. The program aims to curb the spread of TB through faster diagnosis as well as transport samples for HIV testing in areas lacking adequate diagnostic facilities.
Social Media Post: Anthony is 1 of 400 STRiders – Specimen Transport Riders – across the Philippines. On his motorcycle he can easily navigate heavy Manila traffic, speeding up delivery of specimens to labs equipped with GeneXpert diagnostic machines. Faster diagnosis is helping curb the spread of tuberculosis. Read more: https://www.theglobalfund.org/en/stories/2025/2025-09-10-profile-anthony-estomata/
Case Study: Nigeria
Deploying the Latest Tools to Prevent Child Deaths from Malaria
Nigeria is home to a staggering 39% of all global malaria deaths among children under 5 years old.
To combat this tragic loss of life, the Global Fund works with the government, non-governmental organizations, partners and local communities to roll out integrated mass insecticide-treated net and seasonal malaria chemoprevention campaigns (SMC).
In Nigeria’s Kaduna State, the Global Fund supported an integrated campaign that aimed to reach 8.1 million people with insecticide-treated nets and 2.2 million children under 5 with their first dose of SMC.
Social Media Post: Nigeria is home to 39% of all malaria deaths among children under 5 years old. In Nigeria’s Kaduna State, @GlobalFund has supported the mass rollout of insecticide-treated nets to reach 8.1 million people and integrated campaigns to reach 2.2 million children under 5 with their first dose of seasonal malaria chemoprevention. Learn more: https://www.theglobalfund.org/en/stories/2025/2025-09-10-nigeria-deploying-latest-tools-prevent-child-deaths-malaria/
Case Study: West Africa
Bolstering Early Warning Disease Detection
Communities across West Africa continue to face old and new infectious disease threats. In response, health officials, policymakers and health financing partners, including the Global Fund, are working to strengthen disease control capacities by replicating a best practice surveillance model from within the region – Senegal’s Sentinel Syndromic Surveillance System – known as the 4S Network.
Through the West African Regional Laboratory Initiative, the Global Fund is working to build upon the 4S model by establishing similar surveillance activities across West Africa.
Investments made in expanding the network have already proved their worth, detecting numerous viral pathogens including dengue, chikungunya, Crimean Congo hemorrhagic virus and yellow fever – allowing authorities to act rapidly.
Social Media Post: Early detection saves lives. From the remote islands of Guinea-Bissau to regional laboratories in Senegal, @GlobalFund is supporting surveillance networks that stop outbreaks before they spread. Through the West African Regional Laboratory Initiative, countries are detecting outbreaks early, speeding up diagnosis and protecting millions from future health threats. Read more: https://www.theglobalfund.org/en/stories/2025/2025-09-10-bolstering-early-warning-disease-detection-across-west-africa/
Case Study: Ukraine
Delivering Lifesaving Care Despite the War
Ukraine’s health systems have been devastated by war – thousands of hospitals and clinics have been damaged or destroyed, supply chains have been decimated, and millions of people are at risk of being cut off from lifesaving HIV, TB and primary health care services.
Despite these monumental challenges, mobile health teams operated by Alliance for Public Health, with support from the Global Fund and other donors, are delivering lifesaving care to communities hit hardest by the war – and who otherwise would have no access to health services.
Between December 2022 and June 2025, Alliance for Public Health mobile clinics completed 640 missions, reaching nearly 25,000 people in 386 communities.
Social Media Post: Despite the dangers of war, health workers across Ukraine are delivering HIV and TB testing, treatment and other lifesaving care to communities cut off from health services. With @GlobalFund support, mobile teams operated by @allianceforph have completed 640 missions, reaching 25,000 people. Read more: https://www.theglobalfund.org/en/stories/2025/2025-09-10-ukraine-delivering-lifesaving-care-despite-war/
Case Study: Ethiopia
Meet Fanose, Health Extension Worker
Fanose Hirreno is one of Ethiopia’s 40,000 Health Extension Workers delivering lifesaving primary care across the country – educating communities, preventing and testing for diseases like HIV, TB and malaria, supporting treatment, and referring patients when needed.
A child born in Ethiopia today is almost three times more likely to survive past their fifth birthday than a child born in 2000. Thanks in large part to a 71% reduction in under-5 deaths from AIDS, TB and malaria – and to health extension workers like Fanose.
Social Media Post: Fanose is one of Ethiopia’s 40,000 Health Extension Workers educating communities, preventing and testing for diseases like HIV, TB and malaria, supporting treatment, and referring patients when needed. Thanks in part to these community health workers, a child born in Ethiopia today is almost 3x more likely to survive past their 5th birthday than in 2000. Read more: https://www.theglobalfund.org/en/stories/2025/2025-09-10-profile-fanose-hirreno/
Social Media Messages
The @GlobalFund 2025 Results Report is now available. Working together, the Global Fund partnership has saved 70 MILLION lives since 2002. Investing in the Global Fund is one of the most effective ways to save lives, improve the health of many and reinforce global health security. https://www.theglobalfund.org/en/results/
Just Released: 2025 Global Fund Results Report. Working together, the Global Fund partnership has saved 70 MILLION lives since 2002. Investments in health not only save lives – they also drive economic productivity and broader socioeconomic development. https://www.theglobalfund.org/en/results/
The @GlobalFund partnership is delivering on its promise: to save lives from AIDS, TB and malaria. In countries where the Global Fund invests, the combined incidence rate from the three diseases has dropped by 42% since 2002 and the combined death rate by 63%. https://www.theglobalfund.org/en/results/
New @GlobalFund Results: 25.6 million people were on lifesaving antiretroviral therapy for HIV in 2024. Working together, the Global Fund partnership is aligning efforts, scaling proven solutions and delivering impact in the fight against AIDS. https://www.theglobalfund.org/en/results/#hiv
New @GlobalFund Results: 7.4 million people were treated for tuberculosis in 2024. The Global Fund partnership is working hand-in-hand with governments, civil society, the private sector and community-based organizations to make TB services efficient, equitable and effective. https://www.theglobalfund.org/en/results/#tb
New @GlobalFund Results: 162 million mosquito nets were distributed to protect families from malaria in 2024. Working together, the Global Fund partnership is prioritizing local solutions that build long-term resilience to better withstand future threats. https://www.theglobalfund.org/en/results/#malaria
The best global defense against infectious diseases is to contain outbreaks at their source through strong, resilient health systems. @GlobalFund invests in health systems and disease surveillance in more than 100 countries to help detect, track and contain new outbreaks around the world. https://www.theglobalfund.org/en/results/#hcs
The Path Ahead: The Global Fund's Eighth Replenishment
2025 marks the Global Fund’s Eighth Replenishment – a defining moment for global health. This Replenishment is critical to maintain momentum against AIDS, TB and malaria and prevent a resurgence that could undo decades of progress. Without urgent and focused investment, the human, social and economic toll could be devastating.
Investing in the Global Fund partnership means supporting one of the world’s most effective mechanisms to fight infectious diseases. Every dollar we receive drives measurable health outcomes, fuels economic returns and delivers exceptional value for money. We continue to evolve and adapt to the rapidly changing global context, but our ability to succeed amid the current challenges depends on the international community’s resolve to recommit to global health.
Now is the time to mobilize our collective force to protect the gains we have made, save millions more lives, and move with purpose toward a future free from AIDS, TB and malaria.
Data Explorer
Explore data on investments and results in the fight against AIDS, TB and malaria around the world.
The Global Fund invests in smart, effective health programs to end AIDS, TB and malaria as epidemics. The Data Explorer visualizes where our investments come from, where they are and what they achieve by providing pledge and contribution data, grant financial data, and results data at global, regional and country levels.